Dimethyl fumarate (DMFu or DMF) is the methyl ester of fumaric acid. DMF was initially recognised as a very effective hypoxic cell radiosensitiser. The strong disinfection effects makes it widely used as disinfection and mould inhibitor of leather, footwear, textiles AND bamboo products. However, DMF has been found to be an allergic sensitiser at very low concentrations, producing eczema that is difficult to treat.
Other regulations, directives or standards
On 15 May 2012, a restriction of DMFu was added under REACH Annex XVII as follows by the publication of (EU) No 412/2012:
Shall not be used in articles or any parts thereof in concentrations greater than 0,1 mg/kg。
Articles or any parts thereof containing DMF in concentrations greater than 0,1 mg/kg shall not be placed on the market.
It is also noted that the DMFu restriction specified in Oeko-Tex®Standard 100 is consistent with the above.
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